HLA/Immunogenetics Laboratory Profiles

Testing for Individual HLA Alleles

Patients are tested for particular HLA alleles, for use in the diagnosis or treatment of various conditions. The following is a partial listing of HLA/disease or drug hypersensitivity associations.

Disease	Associated HLA Allele(s)
Birdshot Retinopathy Association	HLA-A*29
Ankylosing Spondylitis (and other arthropathies)	HLA-B*27
Behcet’s Disease Association	HLA-B*51
Celiac Association	HLA-DQB102 HLA-DQA105
Narcolepsy Association	DQB1 *0602

Drug Hypersensitivity	Associated HLA Allele(s)
Carbamazepine	B*1502
Abacavir	B*5701
HLA-B*5801 Typing	B*5801

Note: In addition to the above list we can type for any A, B, C, DRB1, DRB3, DRB4, DRB5, DQA1, DQB1, DPB1, DPA1 alleles.

Testing Details for Individual HLA Alleles

Specimen Requirements:
- One 10cc ACD blood (yellow top, solution A or B) tube
Labeling Requirements:
- Specimen must have the patient’s first and last name, a collection date and a unique identifier written on the tube.
Analytic Time:
- See specific test for details.
Testing schedule:
- Monday through Friday

All specimens must be accompanied by a Request for Testing Form

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