Profile or Test Panel
Bleeding Diathesis with a Normal aPTT/PT Profile
Fibrinolysis Evaluation Profile
Method Chromogenic
Test Information Alpha-2-antiplasmin, a naturally-occurring inhibitor of fibrinolysis, is measured using a chromogenic substrate. Levels are reduced in hereditary alpha-2-antiplasmin deficiency, a rare autosomal recessive bleeding disorder. Some heterozygous individuals (40-60%) have mild bleeding tendencies. Acquired deficiencies include liver disease, disseminated intravascular coagulation (DIC), and thrombolytic therapy.
Additional Test Information Normal ranges are included on testing report and can be made available upon request.
Sample Requirements Whole Blood: 3.2% sodium citrated (blue top) OR
frozen plasma
Requested Volume Two 5 ml 3.2%  sodium citrated (blue top) tubes as whole blood OR
frozen plasma in 4 X 1mL aliquots in plastic tubes
Minimum Volume or Pediatric Volume Frozen Plasma: at least 0.5ml in 2 plastic tubes.
Sample Information Whole blood is preferred for testing, but if it is not possible to send whole blood tubes TO ARRIVE HERE WITHIN 2 HOURS of collection, then send frozen plasma. To prepare plasma, centrifuge blue top tubes at 1500g for 15 minutes and remove the plasma and centrifuge a second time at 1500g for an additional 15 minutes. Aliquot approximately 1 ml of plasma into 4 plastic tubes, and freeze.
Shipping Information Whole Blood: Send at ambient temperature (18-25°C) and must be received within the lab in less than or equal to 2 hours after collection.

Frozen Plasma: Send on dry ice.

Send samples to:
Bloodworks Northwest
Attn:Hemostasis Laboratory
921 Terry Ave
Seattle, WA 98104

For additional information, please see Ordering Information

Requisition Form RFT- Hemostasis Reference Laboratory
Transaction Code 3230-04
CPT Codes 85410
Test Schedule Monday – Friday
Turn around Time (analytic time) 10 Business Days
Report/Results Fax number required to receive report

Your gift of blood, time or money saves lives.